Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | TSHR | P16473 | 4/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.45 |
| ▸ | SNCA | P37840 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25427265 | 0.90 | ALDH1A1 (0.67) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL29587490 | 0.85 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL29208381 | 0.85 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL25421576 | 0.82 | TSHR (0.51) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL29208441 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL3461756 | 0.76 | ERCC1 (0.60) | TSHRKLKB1KLK1ERCC1ERCC4 | |
| SCHEMBL29208475 | 0.74 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL14632407 | 0.73 | ALDH1A1 (0.65) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL25425543 | 0.72 | TSHR (0.49) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL6087245 | 0.72 | HTR6 (0.51) | ALDH1A1KDM4ETSHRHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204808-A1 | TARGET ENGAGEMENT ASSAY FOR RAS PROTEINS | Promega Corporation (US) | 2023-07-05 | — | — | EP | disclosed |