Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29208388 | 0.90 | HDAC8 (0.42) | HDAC8HDAC6HDAC1HDAC2HDAC10 | |
| SCHEMBL29208411 | 0.83 | ALDH1A1 (0.48) | HDAC8HDAC6HDAC1HDAC2HDAC10 | |
| SCHEMBL30991824 | 0.82 | BACE1 (0.49) | HDAC8HDAC6HDAC1HDAC2HDAC10 | |
| SCHEMBL24414636 | 0.82 | BACE1 (0.49) | HDAC8HDAC6HDAC1HDAC2HDAC10 | |
| SCHEMBL24414631 | 0.78 | HTR6 (0.57) | HDAC8HDAC6HDAC1HDAC2HDAC10 | |
| SCHEMBL25425543 | 0.77 | TSHR (0.49) | HDAC8HDAC6HDAC1HDAC2HDAC10 | |
| SCHEMBL24414633 | 0.76 | LMNA (0.42) | HDAC8HDAC6HDAC1HDAC2HDAC10 | |
| SCHEMBL30991849 | 0.76 | LMNA (0.42) | HDAC8HDAC6HDAC1HDAC2HDAC10 | |
| SCHEMBL5709288 | 0.73 | TPSAB1 (0.51) | HDAC6HDAC3NCOR2F10PRSS1 | |
| SCHEMBL29208495 | 0.73 | ADA (0.35) | HDAC8HDAC6HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116391129-A | Target binding assays for RAS proteins | 普罗美加公司 | 2023-07-04 | — | — | CN | disclosed |