SCHEMBL29209355

SCHEMBL29209355

C=C(C(=O)N1CCCC1)c1ccccc1Cl

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.50
ALDH1A1 P00352 5/20 0.49
MAPT P10636 3/20 0.49
MEN1 O00255 2/20 0.48
POLB P06746 2/20 0.48
RXFP1 Q9HBX9 1/20 0.47
HPGD P15428 3/20 0.47
NPC1 O15118 1/20 0.47
GLA P06280 1/20 0.47
RAB9A P51151 3/20 0.47
LMNA P02545 2/20 0.47
MAPK1 P28482 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
NPSR1 Q6W5P4 1/20 0.45
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28917069 0.83 CES2 (0.59) KMT2AALDH1A1MAPTMEN1POLB
SCHEMBL28916551 0.81 CES2 (0.57) KMT2AALDH1A1MAPTMEN1POLB
SCHEMBL4171372 0.79 KMT2A (0.73) KMT2AALDH1A1MEN1POLBRXFP1
SCHEMBL4965838 0.79 KMT2A (0.47) KMT2AALDH1A1MAPTMEN1POLB
SCHEMBL29944094 0.77 KMT2A (0.72) KMT2AALDH1A1MEN1POLBRXFP1
SCHEMBL3456393 0.77 KMT2A (0.72) KMT2AALDH1A1MEN1POLBRXFP1
SCHEMBL3454984 0.77 KMT2A (0.72) KMT2AALDH1A1MEN1POLBRXFP1
SCHEMBL18544668 0.77 LMNA (0.50) KMT2AALDH1A1MAPTMEN1POLB
SCHEMBL5177760 0.76 LMNA (0.48) ALDH1A1HPGDLMNASMN1; SMN2L3MBTL1
SCHEMBL30749660 0.76 HSD11B1 (0.42) KMT2AALDH1A1HPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117510291-A Preparation method of acrylamide compound 昆明理工大学 2024-02-06 CN disclosed