Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 3/20 | 0.32 |
| ▸ | TDO2 | P48775 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28502698 | 0.81 | TDO2 (0.45) | TRPA1METAP2JAK2JAK1TYK2 | |
| SCHEMBL29209720 | 0.81 | TDO2 (0.45) | TRPA1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31358022 | 0.73 | NOS1 (0.52) | TRPA1CDK2FLT3IDO1NOS1 | |
| SCHEMBL11577937 | 0.72 | METAP2 (0.39) | TRPA1METAP2METNOS1MAPT | |
| SCHEMBL29520830 | 0.70 | TRPA1 (0.50) | TRPA1METAP2JAK2METCDK2 | |
| SCHEMBL2425031 | 0.69 | NOS1 (0.52) | TRPA1METAP2METTDO2IDO1 | |
| SCHEMBL29209750 | 0.68 | IDO1 (0.30) | IDO1 | |
| SCHEMBL24630042 | 0.67 | TRPA1 (0.40) | TRPA1MAPT | |
| SCHEMBL20001953 | 0.66 | TDO2 (0.37) | TDO2CDK2IDO1KDM4EMEN1 | |
| SCHEMBL31357946 | 0.66 | LRRK2 (0.41) | TRPA1METAP2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024099269-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, USE THEREOF | 华东师范大学 | 2024-05-16 | — | — | WO | disclosed |
| CN-118026880-A | Aryl amide compound, pharmaceutical composition containing same and application thereof | 华东师范大学 | 2024-05-14 | — | — | CN | disclosed |