Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721638 | 0.90 | KMT2A (0.37) | KMT2AATMALDH1A1PKMMEN1 | |
| SCHEMBL29000169 | 0.81 | KMT2A (0.50) | KMT2AATMALDH1A1PKMMEN1 | |
| SCHEMBL1608836 | 0.73 | ALDH1A1 (0.46) | KMT2AALDH1A1MEN1MAPK1L3MBTL1 | |
| SCHEMBL381291 | 0.73 | KMT2A (0.46) | KMT2AATMALDH1A1PKMMEN1 | |
| SCHEMBL15549642 | 0.72 | KMT2A (0.48) | KMT2AATMALDH1A1PKMMEN1 | |
| SCHEMBL20681587 | 0.72 | KMT2A (0.39) | KMT2AATMALDH1A1PKMMEN1 | |
| SCHEMBL18122756 | 0.71 | SMN1; SMN2 (0.38) | KMT2AALDH1A1HPGDPSMB8PSMB5 | |
| SCHEMBL20463167 | 0.71 | KMT2A (0.35) | KMT2AALDH1A1HPGDPSMB8PSMB5 | |
| SCHEMBL27697490 | 0.70 | MGLL (0.30) | PSMB8PSMB5 | |
| SCHEMBL12804228 | 0.70 | HPGD (0.35) | KMT2AALDH1A1MEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999101-A | EGFR-targeting Fc antigen binding fragment-drug conjugates | 默克专利股份公司 | 2024-05-07 | — | — | CN | disclosed |