Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.36 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17265581 | 0.84 | MAPK14 (0.45) | MAPK14KCNN4KCNA5CLK1GSK3B | |
| SCHEMBL12574227 | 0.82 | MAPK14 (0.46) | MAPK14KCNN4KCNA5CLK1GSK3B | |
| SCHEMBL2092638 | 0.79 | GSK3B (0.42) | MAPK14KCNN4KCNA5CLK1GSK3B | |
| SCHEMBL28865856 | 0.78 | HSD17B1 (0.51) | MAPTHSD17B10 | |
| SCHEMBL2092641 | 0.77 | PGR (0.46) | MAPK14KCNN4KCNA5CLK1GSK3B | |
| SCHEMBL21776422 | 0.77 | KMT2A (0.46) | MAPK14KCNN4KCNA5CLK1GSK3B | |
| SCHEMBL11361207 | 0.77 | MAPK14 (0.42) | MAPK14KCNN4KCNA5CLK1GSK3B | |
| SCHEMBL14621860 | 0.76 | SIGMAR1 (0.43) | CLK1ALDH1A1HSD17B10 | |
| SCHEMBL28250211 | 0.76 | GPBAR1 (0.40) | ALDH1A1MAPT | |
| SCHEMBL4935241 | 0.76 | PDK1 (0.44) | MAPK14KCNN4KCNA5CLK1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820221-A | Process for preparing difluoromethylated 2, 4-quinolinedione derivatives | 南宁师范大学 | 2024-04-05 | — | — | CN | disclosed |