Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.46 |
| ▸ | METAP1 | P53582 | 2/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | FCER2 | P06734 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29214291 | 1.00 | METAP2 (0.46) | METAP2METAP1KLK7KLKB1MEN1 | |
| SCHEMBL27076683 | 0.81 | METAP2 (0.65) | METAP2METAP1KLK7MEN1KMT2A | |
| SCHEMBL27076680 | 0.81 | METAP2 (0.65) | METAP2METAP1KLK7MEN1KMT2A | |
| SCHEMBL27076755 | 0.80 | MMP1 (0.47) | METAP2METAP1KLK7KLKB1MEN1 | |
| SCHEMBL27076750 | 0.80 | MMP1 (0.47) | METAP2METAP1KLK7KLKB1MEN1 | |
| SCHEMBL28349261 | 0.79 | KLK7 (0.54) | METAP2METAP1KLK7KLKB1MEN1 | |
| SCHEMBL29068018 | 0.77 | KMT2A (0.50) | METAP2METAP1KLK7MEN1KMT2A | |
| SCHEMBL29068015 | 0.77 | KMT2A (0.50) | METAP2METAP1KLK7MEN1KMT2A | |
| SCHEMBL22987023 | 0.77 | KMT2A (0.51) | MEN1KMT2APSMB1CYP2D6ALDH1A1 | |
| SCHEMBL3511151 | 0.76 | HPGD (0.45) | METAP2METAP1KLK7KLKB1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858867-A | SARS-COV-2 MPRO inhibitor compounds | 赫普泰雅治疗有限公司 | 2024-04-09 | — | — | CN | disclosed |