Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | FCER2 | P06734 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29068015 | 1.00 | KMT2A (0.50) | KMT2AMEN1HPGDUSP2ALDH1A1 | |
| SCHEMBL27076680 | 0.82 | METAP2 (0.65) | KMT2AMEN1HPGDUSP2ALDH1A1 | |
| SCHEMBL27076683 | 0.82 | METAP2 (0.65) | KMT2AMEN1HPGDUSP2ALDH1A1 | |
| SCHEMBL27076750 | 0.81 | MMP1 (0.47) | KMT2AMEN1HPGDUSP2ALDH1A1 | |
| SCHEMBL27076755 | 0.81 | MMP1 (0.47) | KMT2AMEN1HPGDUSP2ALDH1A1 | |
| SCHEMBL8411451 | 0.78 | KMT2A (0.54) | KMT2AMEN1HPGDALDH1A1MMP8 | |
| SCHEMBL8412726 | 0.78 | KMT2A (0.54) | KMT2AMEN1HPGDALDH1A1MMP8 | |
| SCHEMBL8411454 | 0.78 | KMT2A (0.54) | KMT2AMEN1HPGDALDH1A1MMP8 | |
| SCHEMBL5520650 | 0.78 | RAB9A (0.61) | KMT2AMEN1HPGDUSP2ALDH1A1 | |
| SCHEMBL29214293 | 0.77 | METAP2 (0.46) | KMT2AMEN1HPGDUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669727-A | Triazole-pyridinyl substituted azacyclohexylacetic acid compounds as LPA receptor antagonists | 唯久生物有限公司 | 2023-08-29 | — | — | CN | disclosed |