Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8208517 | 0.80 | ALOX15 (0.48) | BLMALOX15NFKB1SMN1; SMN2LMNA | |
| SCHEMBL20791866 | 0.76 | ALOX15 (0.48) | BLMALOX15NFKB1SMN1; SMN2LMNA | |
| SCHEMBL3793592 | 0.76 | SMN1; SMN2 (0.48) | BLMALOX15NFKB1SMN1; SMN2LMNA | |
| SCHEMBL1050340 | 0.76 | NFKB1 (0.48) | BLMALOX15NFKB1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL11439571 | 0.74 | SMN1; SMN2 (0.47) | BLMALOX15NFKB1SMN1; SMN2LMNA | |
| Water SCHEMBL27669910 | 0.74 | NFKB1 (0.47) | BLMALOX15NFKB1SMN1; SMN2LMNA | |
| SCHEMBL7403411 | 0.73 | ALOX15 (0.45) | BLMALOX15NFKB1SMN1; SMN2LMNA | |
| SCHEMBL8149936 | 0.73 | NFKB1 (0.45) | BLMALOX15NFKB1SMN1; SMN2LMNA | |
| SCHEMBL3797821 | 0.73 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9715396 | 0.72 | NFKB1 (0.44) | BLMALOX15NFKB1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107118164-B | Process for the preparation of 5-chloro-6- (chloromethyl) -2,4- (1H, 3H) -pyrimidinedione | 卡硼瑞（北京）科技有限公司 | 2024-05-28 | — | — | CN | claimed |