SCHEMBL29216009

SCHEMBL29216009

CC(C)=CCC1(c2ccccc2)Oc2ccccc2C(=O)C1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 3/20 0.41
IKBKB O14920 3/20 0.41
CYP3A4 P08684 3/20 0.39
ALOX15 P16050 2/20 0.39
ALDH1A1 P00352 3/20 0.34
GLA P06280 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
CYP2C19 P33261 3/20 0.33
HIF1A Q16665 3/20 0.33
LMNA P02545 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C9 P11712 2/20 0.33
ALOX12 P18054 1/20 0.33
MAPT P10636 3/20 0.33
DHODH Q02127 2/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3289417 0.72 CYP3A4 (0.42) HSP90AA1CYP3A4ALOX15ALDH1A1GLA
SCHEMBL142562 0.72 HSP90AA1 (0.41) HSP90AA1IKBKBGLACTDSP1CYP2C9
SCHEMBL28140395 0.70 CYP3A4 (0.47) CYP3A4ALOX15GLACTDSP1CYP2C19
SCHEMBL28459231 0.70 SMN1; SMN2 (0.46) CYP3A4ALOX15ALDH1A1GLACTDSP1
SCHEMBL28320415 0.69 RET (0.41) CYP3A4ALOX15ALDH1A1ALOX12MEN1
SCHEMBL5830003 0.68 IDO1 (0.40) CYP3A4ALOX15ALDH1A1ALOX12IDO1
SCHEMBL7513764 0.68 CYP3A4 (0.42) HSP90AA1CYP3A4ALOX15ALDH1A1GLA
SCHEMBL30912243 0.67 ALDH1A1 (0.39) CYP3A4ALOX15ALDH1A1CYP2C19HIF1A
SCHEMBL31443278 0.65 HSP90AA1 (0.40) HSP90AA1CYP3A4ALOX15ALDH1A1GLA
SCHEMBL4259499 0.64 MAPT (0.41) HSP90AA1IKBKBCYP3A4ALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118047788-A Isopentenyl phenolic compound, and preparation method and application thereof 中国医药工业研究总院有限公司 2024-05-17 CN disclosed