Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4259494 | 1.00 | MAPT (0.41) | MAPTPGRHTR1AADORA3PTGS1 | |
| SCHEMBL2582093 | 0.83 | PTGS2 (0.40) | MAPTPGRHTR1AADORA3PTGS1 | |
| SCHEMBL28881800 | 0.75 | SIGMAR1 (0.39) | ALOX15CYP3A4ALDH1A1CYP2C19SIGMAR1 | |
| SCHEMBL19358635 | 0.74 | BACE1 (0.36) | MAPTCYP1A2CYP2C9HIF1ACYP2C19 | |
| SCHEMBL6561518 | 0.74 | SIGMAR1 (0.45) | MAPTADORA3CYP2C9SMN1; SMN2SIGMAR1 | |
| SCHEMBL29258996 | 0.74 | SIGMAR1 (0.45) | MAPTADORA3CYP2C9SMN1; SMN2SIGMAR1 | |
| SCHEMBL27281924 | 0.74 | SIGMAR1 (0.45) | LMNACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20138521 | 0.73 | CYP19A1 (0.41) | MAPTCYP3A4ALDH1A1SMN1; SMN2HSP90AA1 | |
| SCHEMBL27794644 | 0.72 | SIGMAR1 (0.45) | ADORA3CYP2C9ALDH1A1SIGMAR1HSD17B10 | |
| SCHEMBL15570077 | 0.71 | MAPT (0.47) | MAPTPGRHTR1AADORA3PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107746399-A | The synthetic method of the geranyl flavanones of one oxygen substitution | 宁夏大学 | 2018-03-02 | — | — | CN | disclosed |
| WO-2009014315-A1 | A COMPOSITION THAT IS COMPRISING EXTRACTS, FRACTIONS OR ISOLATED SINGLE COMPOUNDS OF ROBINIA PSEUDO-ACACIA VAR. UMBRACULIFERA | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-01-29 | — | — | WO | disclosed |