SCHEMBL7513764

SCHEMBL7513764

CC[C@@H]1C(=O)c2ccccc2O[C@@]1(O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.42
ALOX15 P16050 1/20 0.42
MAPT P10636 3/20 0.40
NPSR1 Q6W5P4 3/20 0.40
HSP90AA1 P07900 1/20 0.40
GLA P06280 2/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
CYP2C9 P11712 4/20 0.35
CYP2C19 P33261 3/20 0.35
RECQL P46063 2/20 0.35
GRM1 Q13255 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
MAOB P27338 1/20 0.35
ALDH1A1 P00352 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7518905 0.84 NPSR1 (0.41) CYP3A4ALOX15MAPTNPSR1HSP90AA1
SCHEMBL3289417 0.82 CYP3A4 (0.42) CYP3A4ALOX15MAPTNPSR1HSP90AA1
SCHEMBL29130447 0.76 ALOX15 (0.41) CYP3A4ALOX15MAPTNPSR1HSP90AA1
SCHEMBL29130441 0.75 CASP6 (0.45) CYP3A4ALOX15MAPTNPSR1HSP90AA1
SCHEMBL7516218 0.74 MEN1 (0.40) CYP3A4ALOX15MAPTNPSR1HSP90AA1
SCHEMBL2337166 0.71 CYP19A1 (0.43) CYP3A4ALOX15MAPTSMN1; SMN2CYP2C9
SCHEMBL7521676 0.71 MAPT (0.43) CYP3A4ALOX15MAPTNPSR1HSP90AA1
SCHEMBL3306471 0.71 CYP19A1 (0.43) CYP3A4ALOX15MAPTSMN1; SMN2CYP2C9
SCHEMBL28459231 0.71 SMN1; SMN2 (0.46) CYP3A4ALOX15MAPTNPSR1GLA
SCHEMBL3197529 0.71 CYP19A1 (0.46) CYP3A4ALOX15MAPTNPSR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743311-B1 FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME KAO CORP (JP) 2002-02-13 EP disclosed
US-5876703-A CELL DIFFERENTIATION OF HAIR MATRIX CELLS KAO CORPORATION (JP) 1999-03-02 US disclosed
US-5702691-A Flavanonol derivatives and hair-nourishing, hair growing compositions containing the derivatives KAO CORPORATION (JP) 1997-12-30 US disclosed
EP-0743311-A1 FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME Kao Corporation (JP) 1996-11-20 EP disclosed