Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10591059 | 0.90 | MEN1 (0.45) | IAPPP2RX3AKR1B1 | |
| SCHEMBL14354428 | 0.80 | ERN1 (0.39) | IAPPAKR1B1CA2 | |
| SCHEMBL11334965 | 0.80 | FOLH1 (0.43) | IAPPAKR1B1 | |
| SCHEMBL1527068 | 0.79 | IAPP (0.44) | IAPP | |
| SCHEMBL30485631 | 0.78 | IAPP (0.70) | IAPPAKR1B1PTGER1PTGER4PTGER3 | |
| SCHEMBL244943 | 0.78 | IAPP (0.70) | IAPPAKR1B1PTGER1PTGER4PTGER3 | |
| SCHEMBL6998511 | 0.78 | FBP1 (0.47) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL5429057 | 0.77 | HSPA5 (0.50) | AKR1B1KEAP1CA1CA2 | |
| SCHEMBL35529 | 0.77 | AKR1B1 (0.65) | IAPPAKR1B1PTGER1PTGER4PTGER3 | |
| SCHEMBL7128255 | 0.77 | AKR1B1 (0.65) | IAPPAKR1B1PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4346810-A1 | COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF | Unigen, Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| CN-117794534-A | Compositions for modulating cortisol homeostasis and improving sleep quality and methods of use and preparation thereof | 尤尼根公司 | 2024-03-29 | — | — | CN | disclosed |
| WO-2022256624-A1 | COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF | UNIGEN, INC. (US) | 2022-12-08 | — | — | WO | disclosed |