Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TSPO | P30536 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.44 |
| ▸ | CCR2 | P41597 | 2/20 | 0.44 |
| ▸ | EDNRB | P24530 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2214735 | 0.90 | CYP19A1 (0.47) | P2RX4TP53RXFP1CCR2KMT2A | |
| SCHEMBL29217042 | 0.89 | KDM4E (0.53) | P2RX4TP53FABP4CCR2KMT2A | |
| SCHEMBL29217015 | 0.89 | CCR2 (0.48) | TP53TSPOCCR2KMT2AMAPT | |
| SCHEMBL29217013 | 0.88 | MEN1 (0.48) | TP53TSPOFABP4CCR2KMT2A | |
| SCHEMBL27917551 | 0.87 | KDM4E (0.49) | P2RX4TP53TSPOCHRM1KMT2A | |
| SCHEMBL29217030 | 0.85 | FABP4 (0.44) | FABP4MAPT | |
| SCHEMBL29217025 | 0.85 | P2RX4 (0.41) | P2RX4TP53TSPORXFP1KMT2A | |
| SCHEMBL29217006 | 0.84 | LMNA (0.47) | TP53TSPOFABP4EDNRBKMT2A | |
| SCHEMBL27899805 | 0.83 | CNR2 (0.48) | TSPO | |
| SCHEMBL2214060 | 0.82 | ALDH1A1 (0.48) | RXFP1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084903-A | Beta-carboline hydrogen sulfide donor derivative and preparation method and application thereof | 贵州医科大学 | 2024-05-28 | — | — | CN | claimed |
| CN-118084903-A | Beta-carboline hydrogen sulfide donor derivative and preparation method and application thereof | 贵州医科大学 | 2024-05-28 | — | — | CN | disclosed |