Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218556 | 0.88 | L3MBTL1 (0.49) | MAPTL3MBTL1NPC1ALDH1A1MAPK1 | |
| SCHEMBL29218546 | 0.81 | PRSS1 (0.39) | MAPTKMT2A | |
| SCHEMBL29218799 | 0.80 | PTGIR (0.49) | L3MBTL1NPC1ALDH1A1RAB9ABCHE | |
| SCHEMBL29218762 | 0.80 | EPHX1 (0.41) | MAPTL3MBTL1NPC1ALDH1A1MAPK1 | |
| SCHEMBL25039408 | 0.79 | KDM1A (0.35) | MAPTL3MBTL1NPC1ALDH1A1MAPK1 | |
| SCHEMBL29218696 | 0.78 | MGLL (0.44) | CNR2 | |
| SCHEMBL29218839 | 0.78 | USP2 (0.44) | MAPTNPC1ALDH1A1HTTRAB9A | |
| SCHEMBL29218897 | 0.77 | HAO1 (0.45) | MAPTL3MBTL1NPC1ALDH1A1RAB9A | |
| SCHEMBL29218647 | 0.76 | USP2 (0.34) | MAPTALDH1A1CNR2CNR1KMT2A | |
| SCHEMBL29218685 | 0.75 | EML4 (0.36) | MAPTALDH1A1CNR2CNR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |