SCHEMBL29220128

SCHEMBL29220128

CCOC(=O)C(CC=C(C)Cl)(CC(C)C)C(=O)OCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.43
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PKM P14618 3/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 4/20 0.32
HSD17B10 Q99714 3/20 0.32
HPGD P15428 2/20 0.32
MAPK1 P28482 2/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.32
LMNA P02545 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
ALPL P05186 1/20 0.31
POLB P06746 1/20 0.31
ALPI P09923 1/20 0.31
ALPG P10696 1/20 0.31
GRK2 P25098 1/20 0.31
PTPN7 P35236 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29220214 0.85 LMNA (0.39) MMP8ALDH1A1HSD17B10HPGDTSHR
SCHEMBL29220243 0.84 MMP8 (0.32) MMP8MEN1KMT2A
SCHEMBL234014 0.79 MMP8 (0.56) MMP8MEN1KMT2APKMKDM4E
SCHEMBL28248185 0.79 MMP8 (0.46) MMP8MEN1KMT2APKMKDM4E
SCHEMBL29220307 0.78 GRM2 (0.33) ALDH1A1
SCHEMBL2319226 0.78 MMP8 (0.51) MMP8MEN1KMT2APKMKDM4E
SCHEMBL9052824 0.76 MMP8 (0.53) MMP8MEN1KMT2APKMKDM4E
SCHEMBL10836337 0.75 PKM (0.41) MMP8MEN1KMT2APKMKDM4E
SCHEMBL10836349 0.75 PKM (0.41) MMP8MEN1KMT2APKMKDM4E
SCHEMBL10836355 0.75 PKM (0.41) MMP8MEN1KMT2APKMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108878-A Organic polymer carrier and preparation method and application thereof 中国石油天然气股份有限公司 2024-05-31 CN claimed
CN-118108878-A Organic polymer carrier and preparation method and application thereof 中国石油天然气股份有限公司 2024-05-31 CN disclosed