Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.52 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29227088 | 0.89 | LMNA (0.55) | KMT2AMEN1NPSR1TSHRPOLB | |
| SCHEMBL29227120 | 0.88 | PRMT5 (0.53) | PRMT5WDR77KMT2AMEN1NPSR1 | |
| SCHEMBL29227106 | 0.88 | TSHR (0.48) | PRMT5WDR77KMT2AMEN1NPSR1 | |
| SCHEMBL30873435 | 0.81 | ALDH1A1 (0.47) | KMT2ANPSR1TSHRNPC1RAB9A | |
| SCHEMBL29227091 | 0.81 | ALDH1A1 (0.47) | KMT2ANPSR1TSHRNPC1RAB9A | |
| SCHEMBL29227130 | 0.81 | TSHR (0.48) | KMT2ANPSR1TSHRPOLBNPC1 | |
| SCHEMBL30873571 | 0.79 | HRH3 (0.53) | PRMT5WDR77NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30873550 | 0.78 | LMNA (0.57) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL20379519 | 0.77 | TSHR (0.76) | PRMT5WDR77KMT2AMEN1NPSR1 | |
| SCHEMBL29227359 | 0.77 | LMNA (0.45) | PRMT5WDR77KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | claimed |
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | disclosed |