Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29227100 | 0.88 | PRMT5 (0.52) | TSHRNPSR1NPC1HPGDRAB9A | |
| SCHEMBL29227130 | 0.84 | TSHR (0.48) | TSHRNPSR1NPC1HPGDRAB9A | |
| SCHEMBL29227088 | 0.83 | LMNA (0.55) | TSHRNPSR1NPC1HPGDRAB9A | |
| SCHEMBL29227091 | 0.76 | ALDH1A1 (0.47) | TSHRNPSR1NPC1HPGDRAB9A | |
| SCHEMBL30873435 | 0.76 | ALDH1A1 (0.47) | TSHRNPSR1NPC1HPGDRAB9A | |
| SCHEMBL29227120 | 0.76 | PRMT5 (0.53) | TSHRNPSR1NPC1HPGDRAB9A | |
| SCHEMBL15987551 | 0.75 | SIGMAR1 (0.60) | POLBSIGMAR1 | |
| SCHEMBL30873571 | 0.74 | HRH3 (0.53) | NPC1RAB9ASMN1; SMN2MAPTPRMT5 | |
| SCHEMBL29227358 | 0.73 | TSHR (0.53) | TSHRNPSR1NPC1HPGDRAB9A | |
| SCHEMBL30873550 | 0.72 | LMNA (0.57) | HPGDKMT2AKDM4EMAPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | claimed |
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | disclosed |