Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MC4R | P32245 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29227251 | 0.90 | MC4R (0.51) | LMNAMC4RKDM4EMEN1KMT2A | |
| SCHEMBL29227129 | 0.85 | LMNA (0.49) | LMNAMC4RALDH1A1 | |
| SCHEMBL29227144 | 0.85 | LMNA (0.45) | LMNAMC4RALDH1A1 | |
| SCHEMBL29227194 | 0.84 | DRD2 (0.51) | LMNAMC4RKDM4EMEN1KMT2A | |
| SCHEMBL29227161 | 0.84 | LMNA (0.52) | LMNAMC4RKDM4EMEN1KMT2A | |
| SCHEMBL29227101 | 0.84 | LMNA (0.55) | HRH3LMNAMC4RKDM4EMEN1 | |
| SCHEMBL29227384 | 0.82 | ABCB1 (0.46) | HRH3LMNAMC4R | |
| SCHEMBL29227077 | 0.82 | LMNA (0.57) | HRH3LMNAKDM4EMEN1KMT2A | |
| SCHEMBL29227087 | 0.81 | LMNA (0.56) | HRH3LMNAMC4RKDM4EMEN1 | |
| SCHEMBL29227228 | 0.80 | LMNA (0.60) | LMNAKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | disclosed |