Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | MC4R | P32245 | 7/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29227129 | 0.92 | LMNA (0.49) | LMNADRD2DRD3MC4RALDH1A1 | |
| SCHEMBL29227251 | 0.89 | MC4R (0.51) | LMNAMC4R | |
| SCHEMBL29227194 | 0.87 | DRD2 (0.51) | LMNADRD2DRD3MC4R | |
| SCHEMBL29227249 | 0.85 | HRH3 (0.48) | LMNAMC4RALDH1A1 | |
| SCHEMBL29227384 | 0.84 | ABCB1 (0.46) | LMNADRD3MC4RKCNH2 | |
| SCHEMBL29227161 | 0.83 | LMNA (0.52) | LMNAMC4R | |
| SCHEMBL29227128 | 0.83 | LMNA (0.52) | LMNAFAAHDRD2CNR1DRD3 | |
| SCHEMBL29227228 | 0.79 | LMNA (0.60) | LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29227124 | 0.77 | MC4R (0.61) | LMNAMC4R | |
| SCHEMBL29227170 | 0.73 | ALDH1A1 (0.44) | MC4RHTR6KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | disclosed |