Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOST | Q9BQB4 | 1/20 | 0.54 |
| ▸ | FPGS | Q05932 | 2/20 | 0.53 |
| ▸ | NOS1 | P29475 | 3/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | ATIC | P31939 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | GART | P22102 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofolate SCHEMBL4535490 | 0.84 | SOST (0.78) | SOSTFPGSATICDHFRGART | |
| Tetrahydrofolate SCHEMBL82453 | 0.84 | SOST (0.78) | SOSTFPGSATICDHFRGART | |
| Tetrahydrofolate SCHEMBL21194977 | 0.84 | SOST (0.78) | SOSTFPGSATICDHFRGART | |
| Tetrahydrofolate SCHEMBL15263902 | 0.84 | SOST (0.78) | SOSTFPGSATICDHFRGART | |
| Tetrahydrofolate SCHEMBL8031 | 0.84 | SOST (0.78) | SOSTFPGSATICDHFRGART | |
| Tetrahydrofolate SCHEMBL6880950 | 0.84 | SOST (0.78) | SOSTFPGSATICDHFRGART | |
| Tetrahydrofolate SCHEMBL159230 | 0.84 | SOST (0.78) | SOSTFPGSATICDHFRGART | |
| SCHEMBL30424027 | 0.83 | SOST (0.70) | SOSTFPGSNOS1NOS3NOS2 | |
| SCHEMBL2922792 | 0.83 | SOST (0.70) | SOSTFPGSNOS1NOS3NOS2 | |
| Tetrahydrofolate SCHEMBL19376762 | 0.83 | SOST (0.77) | SOSTFPGSATICDHFRGART |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1974047-B1 | PROCESS FOR REGIOSELECTIVE N(5)-FORMYLATION OF (6S)-5,6,7,8-TETRAHYDRO-PTEROIC ACID AND DERIVATIVES THEREOF | CERBIOS PHARMA SA (CH) | 2010-09-01 | — | — | EP | claimed |
| EP-1974047-B1 | PROCESS FOR REGIOSELECTIVE N(5)-FORMYLATION OF (6S)-5,6,7,8-TETRAHYDRO-PTEROIC ACID AND DERIVATIVES THEREOF | CERBIOS PHARMA SA (CH) | 2010-09-01 | — | — | EP | disclosed |
| EP-1974047-B1 | PROCESS FOR REGIOSELECTIVE N(5)-FORMYLATION OF (6S)-5,6,7,8-TETRAHYDRO-PTEROIC ACID AND DERIVATIVES THEREOF | CERBIOS PHARMA SA (CH) | 2010-09-01 | — | — | EP | disclosed |
| EP-1974047-A2 | PROCESS FOR REGIOSELECTIVE N(5)-FORMYLATION OF (6S)-5,6,7,8-TETRAHYDRO-PTEROIC ACID AND DERIVATIVES THEREOF | Cerbios-Pharma S.A. (CH) | 2008-10-01 | — | — | EP | disclosed |
| EP-1974047-A2 | PROCESS FOR REGIOSELECTIVE N(5)-FORMYLATION OF (6S)-5,6,7,8-TETRAHYDRO-PTEROIC ACID AND DERIVATIVES THEREOF | Cerbios-Pharma S.A. (CH) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007082402-B1 | PROCESS FOR REGIOSELECTIVE N(5)-FORMYLATION OF (6S)-5,6,7,8-TETRAHYDROPTEROIC ACID AND DERIVATIVES THEREOF | CERBIOS PHARMA SA (CH) | 2008-01-03 | — | — | WO | disclosed |
| WO-2007082402-B1 | PROCESS FOR REGIOSELECTIVE N(5)-FORMYLATION OF (6S)-5,6,7,8-TETRAHYDROPTEROIC ACID AND DERIVATIVES THEREOF | CERBIOS PHARMA SA (CH) | 2008-01-03 | — | — | WO | disclosed |
| WO-2007082402-A3 | PROCESS FOR REGIOSELECTIVE N(5)-FORMYLATION OF (6S)-5,6,7,8-TETRAHYDROPTEROIC ACID AND DERIVATIVES THEREOF | CERBIOS PHARMA SA (CH) | 2007-11-15 | — | — | WO | disclosed |
| WO-2007082402-A3 | PROCESS FOR REGIOSELECTIVE N(5)-FORMYLATION OF (6S)-5,6,7,8-TETRAHYDROPTEROIC ACID AND DERIVATIVES THEREOF | CERBIOS PHARMA SA (CH) | 2007-11-15 | — | — | WO | disclosed |
| WO-2007082402-A2 | PROCESS FOR REGIOSELECTIVE N(5)-FORMYLATION OF (6S)-5,6,7,8-TETRAHYDROPTEROIC ACID AND DERIVATIVES THEREOF | CERBIOS-PHARMA S.A. (CH) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007082402-A2 | PROCESS FOR REGIOSELECTIVE N(5)-FORMYLATION OF (6S)-5,6,7,8-TETRAHYDROPTEROIC ACID AND DERIVATIVES THEREOF | CERBIOS-PHARMA S.A. (CH) | 2007-07-26 | — | — | WO | disclosed |