Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOST | Q9BQB4 | 1/20 | 0.78 |
| ▸ | FPGS | Q05932 | 2/20 | 0.69 |
| ▸ | ATIC | P31939 | 2/20 | 0.60 |
| ▸ | GART | P22102 | 4/20 | 0.58 |
| ▸ | DHFR | P00374 | 2/20 | 0.57 |
| ▸ | MTHFD1 | P11586 | 2/20 | 0.54 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TYMS | P04818 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofolate SCHEMBL15263902 | 1.00 | SOST (0.78) | SOSTFPGSATICGARTDHFR | |
| Tetrahydrofolate SCHEMBL21194977 | 1.00 | SOST (0.78) | SOSTFPGSATICGARTDHFR | |
| Tetrahydrofolate SCHEMBL4535490 | 1.00 | SOST (0.78) | SOSTFPGSATICGARTDHFR | |
| Tetrahydrofolate SCHEMBL8031 | 1.00 | SOST (0.78) | SOSTFPGSATICGARTDHFR | |
| Tetrahydrofolate SCHEMBL159230 | 1.00 | SOST (0.78) | SOSTFPGSATICGARTDHFR | |
| Tetrahydrofolate SCHEMBL6880950 | 1.00 | SOST (0.78) | SOSTFPGSATICGARTDHFR | |
| Tetrahydrofolate SCHEMBL3445556 | 0.99 | SOST (0.77) | SOSTFPGSATICGARTDHFR | |
| Tetrahydrofolate SCHEMBL21248600 | 0.99 | SOST (0.77) | SOSTFPGSATICGARTDHFR | |
| Tetrahydrofolate SCHEMBL19376762 | 0.99 | SOST (0.77) | SOSTFPGSATICGARTDHFR | |
| Tetrahydrofolate SCHEMBL3404283 | 0.99 | SOST (0.77) | SOSTFPGSATICGARTDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 13419 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747627-A1 | METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS | Matterworks Inc (US) | 2026-05-27 | — | — | EP | claimed |
| WO-2026104625-A1 | LEVERAGING CIRCULATING ORAL MICROBIOME VESICLE-ASSOCIATED PROTEINS FOR THE DIAGNOSIS AND PROGNOSIS OF MIXED DEMENTIAS | INSTITUT DE RECERCA BIOMÈDICA DE LLEIDA - FUNDACIO DR. PIFARRE (ES) | 2026-05-21 | — | — | WO | claimed |
| EP-4745575-A1 | LEVERAGING CIRCULATING ORAL MICROBIOME VESICLE-ASSOCIATED PROTEINS FOR THE DIAGNOSIS AND PROGNOSIS OF MIXED DEMENTIAS | Institut de Recerca Biomèdica de Lleida Fundació Dr Pifarré (ES) | 2026-05-20 | — | — | EP | claimed |
| CN-122061192-A | Electrochemical reaction device, method for electrochemical reduction of disulfide bond and application thereof | 嘉庚创新实验室 | 2026-05-19 | — | — | CN | claimed |
| CN-122056283-A | Pesticide composition for improving sensitivity of agricultural pests to pesticide and application thereof | 华中农业大学 | 2026-05-19 | — | — | CN | claimed |
| WO-2026099900-A1 | A METHOD FOR CO-UTILIZATION OF METHANE AND CARBON DIOXIDE AND SYSTEM THEREOF | STRING BIO PRIVATE LIMITED (IN) | 2026-05-15 | — | — | WO | claimed |
| US-20260117270-A1 | TETRAHYDROFOLATE METHYLTRANSFERASE MUTANT, ENCODING GENE AND APPLICATIONS THEREOF | ZHEJIANG SHENGDA BIO-PHARM CO., LTD. (CN) | 2026-04-30 | — | — | US | claimed |
| US-12600974-B2 | Genetically engineered microorganism capable of growing on formate, methanol, methane or CO2 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2026-04-14 | — | — | US | claimed |
| US-20260048054-A1 | ALPHA POLYGLUTAMATED TETRAHYDROFOLATES AND USES THEREOF | L E A F HOLDINGS GROUP LLC (US) | 2026-02-19 | — | — | US | claimed |
| EP-4692363-A1 | METHOD FOR PRODUCING METHYL COMPOUND | Mitsubishi Chemical Corporation (JP) | 2026-02-11 | — | — | EP | claimed |
| EP-0217862-A1 | $i(IN VITRO) SYNTHESIS OF L-TRYPTOPHAN | GENEX CORPORATION (US) | 1987-04-15 | — | — | EP | claimed |
| WO-1986005515-A1 | IN VITRO SYNTHESIS OF L-TRYPTOPHAN | GENEX CORPORATION (US) | 1986-09-25 | — | — | WO | claimed |
| EP-0185824-A1 | Stabilization of tetrahydrofolic acid and serine hydroxymethyltransferase in reaction mixtures for the enzymatic cynthesis of L-serine | GENEX CORPORATION (US) | 1986-07-02 | — | — | EP | claimed |
| EP-0181902-A1 | NEW COMPOSITIONS OF LIPOSOMES HAVING A SPECIFIC ACTION WITH REGARD TO THE PROLIFERATION OF GIVEN CELLS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1986-05-28 | — | — | EP | claimed |
| EP-0179654-A2 | Process for the preparation of 5,6,7,8-tetrahydrofolic acid | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1986-04-30 | — | — | EP | claimed |
| EP-0165044-A2 | Method of reacting an aldehyde- containing compound with a nucleophilic compound | GENEX CORPORATION (US) | 1985-12-18 | — | — | EP | claimed |
| WO-1985005453-A1 | NEW COMPOSITIONS OF LIPOSOMES HAVING A SPECIFIC ACTION WITH REGARD TO THE PROLIFERATION OF GIVEN CELLS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE M (FR) | 1985-12-05 | — | — | WO | claimed |
| US-4372874-A | Stabilization of hydrolysis prone labile organic reagents in liquid media | MEDICAL ANALYSIS SYSTEMS, INC. | 1983-02-08 | — | — | US | claimed |
| US-4206307-A | SODIUM BOROHYDRIDE, NUETRALIZATION, ASCORBID ACID AS ANTIOXIDANT | UNITED STATES OF AMERICA (US) | 1980-06-03 | — | — | US | claimed |
| US-4148999-A | 5-FORMYL-TETRAHYDROFOLIC ACID | THE GOVERNMENT OF THE UNITED STATES OF AMERICA (US) | 1979-04-10 | — | — | US | claimed |