Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.39 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | LCAT | P04180 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22129474 | 0.81 | PDE10A (0.46) | PANK3KMT2APDE10A | |
| SCHEMBL23044953 | 0.81 | GPR119 (0.47) | ACACB | |
| SCHEMBL29227971 | 0.78 | ACACB (0.43) | ACACBPANK3CHRNA7LCATSMN1; SMN2 | |
| SCHEMBL30932097 | 0.78 | ACACB (0.43) | ACACBPANK3CHRNA7LCATSMN1; SMN2 | |
| SCHEMBL2510938 | 0.73 | GPR119 (0.39) | ACACBJAK2JAK1TYK2KMT2A | |
| SCHEMBL6576692 | 0.71 | KDM4E (0.55) | KMT2AKDM4ELMNA | |
| SCHEMBL30932095 | 0.70 | CHRNA7 (0.48) | ACACBPANK3CHRNA7LCATSMN1; SMN2 | |
| SCHEMBL22129464 | 0.69 | SMO (0.41) | — | |
| SCHEMBL27848379 | 0.69 | PANK3 (0.54) | ACACBPANK3LCATSMN1; SMN2KMT2A | |
| SCHEMBL12240393 | 0.68 | CHRNA7 (0.50) | PANK3CHRNA7LCATSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409333-B | Phenylpyrrolidine compounds | 武汉人福创新药物研发中心有限公司 | 2024-06-14 | — | — | CN | disclosed |