Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29228259 | 0.92 | CSNK2A1 (0.37) | PPARAPPARGPPARD | |
| SCHEMBL29228413 | 0.91 | PPARA (0.40) | PPARAALDH1A1S1PR1PPARGPPARD | |
| SCHEMBL29121231 | 0.90 | ERN1 (0.39) | ERN1PPARARORCSMN1; SMN2LMNA | |
| SCHEMBL28828443 | 0.90 | ERN1 (0.39) | ERN1PPARARORCSMN1; SMN2LMNA | |
| SCHEMBL29228281 | 0.89 | PTGS2 (0.38) | LMNAS1PR1KMT2AMEN1PTGS1 | |
| SCHEMBL29228412 | 0.88 | KDM1A (0.37) | ALDH1A1MAPTCYP1A2CYP2C19KCNH2 | |
| SCHEMBL29228228 | 0.86 | SLC6A3 (0.36) | — | |
| SCHEMBL27200846 | 0.86 | KMO (0.39) | PPARARORCLMNAS1PR1KMT2A | |
| SCHEMBL29121303 | 0.86 | KMO (0.39) | PPARARORCLMNAS1PR1KMT2A | |
| SCHEMBL29121198 | 0.85 | PPARD (0.40) | PPARAALDH1A1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746422-B | Derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-03-12 | — | — | CN | claimed |
| CN-114746422-A | Novel derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2022-07-12 | — | — | CN | claimed |
| CN-114746422-B | Derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-03-12 | — | — | CN | disclosed |
| CN-114746422-A | Novel derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2022-07-12 | — | — | CN | disclosed |