Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | DTYMK | P23919 | 1/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30164149 | 1.00 | OPRD1 (0.35) | OPRD1OPRK1F2RL1POLBNR1H2 | |
| SCHEMBL30918528 | 0.80 | PARP1 (0.48) | OPRD1OPRK1POLBKDM4EALDH1A1 | |
| SCHEMBL29232324 | 0.80 | PARP1 (0.48) | OPRD1OPRK1POLBKDM4EALDH1A1 | |
| SCHEMBL14813528 | 0.79 | ALDH1A1 (0.45) | OPRD1OPRK1NR1H2NR1H3ALDH1A1 | |
| SCHEMBL4494038 | 0.76 | SMN1; SMN2 (0.51) | POLBKDM4EALDH1A1 | |
| SCHEMBL4513476 | 0.73 | ALDH1A1 (0.41) | OPRD1OPRK1NR1H2NR1H3KDM4E | |
| SCHEMBL18291493 | 0.73 | GPR119 (0.38) | OPRD1OPRK1NR1H2SPRGPR119 | |
| SCHEMBL31114254 | 0.73 | POLB (0.41) | OPRD1OPRK1POLBJAK2JAK1 | |
| SCHEMBL21150506 | 0.73 | CTSK (0.39) | F2RL1NR1H2NR1H3ALDH1A1CHRM2 | |
| SCHEMBL20305061 | 0.72 | HDAC1 (0.53) | POLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159530-A | Compounds for the treatment of pain, in particular neuropathic pain and/or other diseases or disorders associated with AT2R and/or AT2R mediated signalling | 康福治疗有限公司 | 2024-06-07 | — | — | CN | disclosed |