SCHEMBL29233452

SCHEMBL29233452

CCC(=O)On1cc(Cl)c(C)n1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.34
TP53 P04637 1/20 0.33
PDE4B Q07343 1/20 0.33
MAP3K14 Q99558 1/20 0.33
ALDH1A1 P00352 3/20 0.32
TSHR P16473 2/20 0.32
MAPK1 P28482 1/20 0.32
LMNA P02545 3/20 0.32
BAZ2B Q9UIF8 1/20 0.32
BAZ2A Q9UIF9 1/20 0.32
HPGD P15428 3/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2C19 P33261 2/20 0.32
BLM P54132 1/20 0.32
WRN Q14191 1/20 0.32
HIF1A Q16665 1/20 0.32
HTT P42858 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
NPC1 O15118 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29233431 0.71 LMNA (0.36) MAPTALDH1A1TSHRMAPK1LMNA
Ammonia Solution, Strong SCHEMBL22574515 0.69 L3MBTL1 (0.35) MAPTALDH1A1TSHRLMNAHTT
SCHEMBL11494319 0.65 HTT (0.45) MAPTALDH1A1LMNAHTTMEN1
SCHEMBL11556929 0.63 KMT2A (0.32) MAPTTSHRLMNAHPGDCYP2C19
SCHEMBL27646906 0.63 NOTUM (0.40) MAPTALDH1A1HPGDCYP1A2CYP2C19
SCHEMBL8508665 0.62 PDE4B (0.49) MAPTPDE4BALDH1A1MAPK1LMNA
Hydrochloric Acid SCHEMBL11558888 0.62 MEN1 (0.33) MAPTALDH1A1MAPK1LMNAHPGD
SCHEMBL6862765 0.61
SCHEMBL601253 0.61 FDPS (0.33) ALDH1A1TSHRLMNAHPGDCYP1A2
SCHEMBL27669704 0.61 ALDH1A1 (0.32) ALDH1A1HPGDCYP1A2CYP2C19BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117964636-B Triazolopyrimidines method for synthesizing compound 上海陶术生物科技股份有限公司 2025-03-21 CN disclosed
CN-117964636-A Synthesis method of triazolopyrimidine compound 上海陶术生物科技有限公司 2024-05-03 CN disclosed