Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480252 | 0.77 | PTGS2 (0.54) | PTGS2PTGS1HSD17B10 | |
| SCHEMBL27855491 | 0.77 | OGG1 (0.40) | HPGDKDM4EHSD17B10LMNAPOLB | |
| SCHEMBL13437655 | 0.76 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL11622203 | 0.75 | PTGS2 (0.51) | PTGS2PTGS1KDM4EHSD17B10 | |
| SCHEMBL7469586 | 0.72 | PTGS2 (0.46) | PTGS2PTGS1HPGDKDM4ELMNA | |
| Sulfamide SCHEMBL4639731 | 0.72 | PTGS2 (0.82) | PTGS2PTGS1 | |
| SCHEMBL11623751 | 0.71 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL14278512 | 0.70 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL215075 | 0.69 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL215038 | 0.69 | PTGS2 (1.00) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557904-B | Synthetic method suitable for large-scale production of 5, 7-bis (trifluoromethyl) quinazoline-2, 4-dione | 天津药明康德新药开发有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-115557904-B | Synthetic method suitable for large-scale production of 5, 7-bis (trifluoromethyl) quinazoline-2, 4-dione | 天津药明康德新药开发有限公司 | 2024-03-19 | — | — | CN | disclosed |