Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SDHB | P21912 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PDE6D | O43924 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | USP1 | O94782 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9940255 | 0.90 | NR1H2 (0.48) | PTGS2PTGS1BRD4ALDH1A1LMNA | |
| SCHEMBL10177495 | 0.90 | SDHB (0.42) | PTGS2PTGS1BRD4SDHBSMN1; SMN2 | |
| SCHEMBL13100054 | 0.86 | PTGS2 (0.61) | PTGS2PTGS1SDHB | |
| SCHEMBL27914819 | 0.84 | BRD4 (0.46) | BRD4ALDH1A1LMNAGAACASP3 | |
| SCHEMBL11622203 | 0.84 | PTGS2 (0.51) | PTGS2PTGS1NR1H3SMN1; SMN2USP1 | |
| SCHEMBL16660862 | 0.84 | DGAT1 (0.58) | PTGS2PTGS1BRD4SDHBSMN1; SMN2 | |
| SCHEMBL29194233 | 0.82 | DRD2 (0.47) | ALDH1A1SDHBSMN1; SMN2USP1RAB9A | |
| SCHEMBL11623751 | 0.80 | PTGS2 (0.48) | PTGS2PTGS1NR1H3SMN1; SMN2RAB9A | |
| SCHEMBL1912768 | 0.78 | TSHR (0.49) | PTGS2PTGS1ALDH1A1NR1H3KDM4E | |
| SCHEMBL9940251 | 0.78 | DGAT1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1153766-C | Nitroketone compound, its preparing process and pharmaceutical composition containing same | ɪά��ʵ���� | 2004-06-16 | — | — | CN | disclosed |
| EP-0967207-B1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-09-11 | — | — | EP | disclosed |
| US-6034250-A | ANTIOXIDANTS | ADIR ET COMPAGNIE (FR) | 2000-03-07 | — | — | US | disclosed |
| EP-0967207-A1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-12-29 | — | — | EP | disclosed |