Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19900027 | 0.94 | PTGDR (0.40) | PTGDRPTGDR2KDM4EMEN1MAPT | |
| SCHEMBL27172075 | 0.84 | PTGDR (0.50) | PTGDRPTGDR2KDM4EMEN1MAPT | |
| SCHEMBL20412793 | 0.80 | TP53 (0.45) | MEN1MAPTKMT2AUSP30KRAS | |
| SCHEMBL15567556 | 0.78 | NR4A2 (0.47) | PTGDRPTGDR2KDM4EMAPTALDH1A1 | |
| SCHEMBL27172001 | 0.78 | FPR2 (0.48) | USP30 | |
| SCHEMBL27171876 | 0.78 | FPR2 (0.48) | USP30 | |
| SCHEMBL30074465 | 0.78 | FPR2 (0.48) | USP30 | |
| SCHEMBL1620627 | 0.77 | PTGDR (0.55) | PTGDRPTGDR2KDM4EMEN1MAPT | |
| SCHEMBL16423371 | 0.77 | GAA (0.40) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL4628583 | 0.77 | CES2 (0.41) | PTGDR2KDM4EGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250145607-A1 | Modulators of CAMKK2 as Ligand Directed Degraders | CELGENE CORPORATION (US) | 2025-05-08 | — | — | US | disclosed |
| EP-4412999-A1 | MODULATORS OF CAMKK2 AS LIGAND DIRECTED DEGRADERS | Celgene Corporation (US) | 2024-08-14 | — | — | EP | disclosed |
| CN-118076603-A | CAMKK2 modulators as ligand-directed degradants | 细胞基因公司 | 2024-05-24 | — | — | CN | disclosed |
| WO-2023059873-A1 | MODULATORS OF CAMKK2 AS LIGAND DIRECTED DEGRADERS | CELGENE CORPORATION (US) | 2023-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145607-A1 | Modulators of CAMKK2 as Ligand Directed Degraders | CAMKK2, CAMKK1, CAMK1D | PTGDR 1013/4885PTGDR2 719/4885KDM4E 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.