SCHEMBL29236644

SCHEMBL29236644

CNc1nc2c(N)cccc2o1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.44
HTR3A P46098 1/20 0.41
F2RL3 Q96RI0 2/20 0.38
KDM4E B2RXH2 3/20 0.35
MAPT P10636 3/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALOX15 P16050 1/20 0.34
FBP1 P09467 1/20 0.34
ALDH1A1 P00352 2/20 0.33
PARP1 P09874 1/20 0.33
GALK1 P51570 1/20 0.32
NPC1 O15118 2/20 0.32
PKM P14618 2/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
GAA P10253 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19808453 0.79 ELANE (0.44) ELANEHTR3AKDM4EMAPTHSD17B10
SCHEMBL8567637 0.78 RAB9A (0.58) ELANEKDM4EMAPTTDP1ALOX15
SCHEMBL3183685 0.76 ELANE (0.59) ELANEF2RL3KDM4EMAPTHIF1A
SCHEMBL1095484 0.75 MAPT (0.41) ELANEHTR3AF2RL3KDM4EMAPT
SCHEMBL1005664 0.73 HTR3A (0.54) ELANEHTR3AKDM4EFBP1ALDH1A1
SCHEMBL28435873 0.72 ELANE (0.39) ELANEF2RL3KDM4EMAPTHIF1A
SCHEMBL9390262 0.72 ELANE (0.39) ELANEF2RL3KDM4EMAPTHIF1A
SCHEMBL1917749 0.71 ELANE (0.39) ELANEF2RL3KDM4EMAPTHIF1A
SCHEMBL1005701 0.71 TOP2A (0.56) ELANEHTR3AKDM4EMAPTHSD17B10
SCHEMBL10825753 0.70 NPC1 (0.51) F2RL3KDM4EMAPTHIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118186779-A Sizing agent for enhancing PBO fiber composite material interface, and preparation method and application thereof 中国科学院化学研究所 2024-06-14 CN disclosed