Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718845 | 0.82 | RAB9A (0.60) | RAB9ANPC1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL21776904 | 0.81 | NPC1 (0.58) | RAB9ANPC1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL29236644 | 0.78 | ELANE (0.44) | RAB9ANPC1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL31213015 | 0.77 | ALDH1A1 (0.54) | RAB9ANPC1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL1005268 | 0.77 | NPC1 (0.54) | RAB9ANPC1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL2658434 | 0.74 | NPC1 (1.00) | RAB9ANPC1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL33525242 | 0.74 | IL6 (0.45) | RAB9ANPC1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL1003521 | 0.73 | TOP2A (0.58) | RAB9ANPC1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL7109574 | 0.71 | RAB9A (0.53) | RAB9ANPC1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL31433078 | 0.71 | RAB9A (0.53) | RAB9ANPC1GAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998024776-A1 | PREPARATION OF AN AMINOARYLAMINOARAZOLE | THE DOW CHEMICAL COMPANY (US) | 1998-06-11 | — | — | WO | disclosed |
| US-5739344-A | Preparation of an aminoarylaminoarazole | THE DOW CHEMICAL COMPANY (US) | 1998-04-14 | — | — | US | disclosed |