Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28699281 | 0.93 | CAMK2D (0.45) | DRD2CAMK2DTDP1MEN1GAA | |
| SCHEMBL26111115 | 0.86 | DRD2 (0.41) | DRD2TDP1ALDH1A1GFERMEN1 | |
| SCHEMBL31612833 | 0.81 | DRD2 (0.41) | DRD2SUV39H2MEN1KMT2A | |
| SCHEMBL19224563 | 0.80 | TNF (0.36) | CAMK2DFPR3FPR2 | |
| SCHEMBL22759403 | 0.79 | FPR3 (0.34) | DRD2FPR3FPR2 | |
| SCHEMBL4610689 | 0.79 | FPR2 (0.38) | ALDH1A1GAAFPR2 | |
| SCHEMBL31082278 | 0.78 | DRD2 (0.39) | DRD2CAMK2DTDP1SUV39H2ALDH1A1 | |
| SCHEMBL4897978 | 0.77 | DRD2 (0.45) | DRD2CAMK2DTDP1ALDH1A1GFER | |
| SCHEMBL20562649 | 0.77 | KDM4E (0.38) | ALDH1A1 | |
| SCHEMBL15230862 | 0.77 | SMN1; SMN2 (0.37) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946098-A | Pyrimidine PLK1 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-04-30 | — | — | CN | disclosed |