Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9068754 | 0.77 | PNMT (0.38) | PNMTDRD2SLC6A2SLC6A4NPC1 | |
| Hydrochloric Acid SCHEMBL30923542 | 0.73 | CHRM2 (0.30) | — | |
| SCHEMBL29566807 | 0.72 | TSHR (0.54) | GPR3DRD2SLC6A2HTR2AHTR2C | |
| SCHEMBL11843513 | 0.72 | TSHR (0.54) | GPR3DRD2SLC6A2HTR2AHTR2C | |
| SCHEMBL27816258 | 0.71 | HTR7 (0.41) | GPR3PNMTDRD2SLC6A2HTR2A | |
| SCHEMBL27835853 | 0.70 | PNMT (0.43) | PNMTDRD2SLC6A2HTR2AHTR2C | |
| SCHEMBL28524377 | 0.70 | PNMT (0.40) | GPR3PNMTNPC1RAB9ASIGMAR1 | |
| SCHEMBL5012393 | 0.70 | HTR2A (0.56) | GPR3DRD2SLC6A2HTR2AHTR2C | |
| SCHEMBL28825910 | 0.70 | HTR2A (0.56) | GPR3DRD2SLC6A2HTR2AHTR2C | |
| SCHEMBL28051679 | 0.70 | HTR2A (0.56) | GPR3DRD2SLC6A2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118251454-A | Resin composition and use thereof | 三井化学株式会社 | 2024-06-25 | — | — | CN | disclosed |
| CN-114514277-B | Ethylene-alpha-olefin copolymer composition and use thereof | 三井化学株式会社 | 2024-06-18 | — | — | CN | disclosed |
| CN-115003757-B | Polyamide composition | 三井化学株式会社 | 2024-05-14 | — | — | CN | disclosed |