Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.52 |
| ▸ | SKP1 | P63208 | 1/20 | 0.52 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.52 |
| ▸ | ACACB | O00763 | 7/20 | 0.51 |
| ▸ | ACACA | Q13085 | 6/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29311592 | 0.89 | CKS1B (0.53) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL4695534 | 0.89 | ACACB (0.53) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL5653703 | 0.88 | CKS1B (0.53) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL12916519 | 0.87 | GPR119 (0.57) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL16394312 | 0.86 | CKS1B (0.53) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL8222029 | 0.86 | CKS1B (0.53) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL4116060 | 0.85 | CKS1B (0.64) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL948774 | 0.84 | CKS1B (0.52) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL803332 | 0.83 | CKS1B (0.56) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL9984934 | 0.83 | CKS1B (0.56) | CKS1BSKP1SKP2ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250381196-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING KIDNEY DISEASES AND KIDNEY-RELATED DISEASES | SHANGHAI YAO YUAN BIOTECHNOLOGY CO LTD (CN) | 2025-12-18 | — | — | US | disclosed |
| US-20250241908-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING ATHEROSCLEROSIS AND RELATED DISEASES | NINGBO MEISHAN BONDED PORT AREA ZHEJIANG UNITED INVESTMENT MANAGEMENT CO., LTD. (CN) | 2025-07-31 | — | — | US | disclosed |
| CN-119997953-A | Alpha protein kinase 1 inhibitors for the treatment of kidney diseases and kidney related diseases | 上海药苑生物科技有限公司 | 2025-05-13 | — | — | CN | disclosed |
| US-20240226094-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING KAWASAKI DISEASE | XU, Cong (CN) | 2024-07-11 | — | — | US | disclosed |
| CN-118103045-A | Alpha protein kinase 1 inhibitors for the treatment of kawasaki disease | 上海药苑生物科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| US-20240109853-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS AND METHODS OF USE | TIANJIN HONGKE BAISHI QIXIN VENTURE CAPITAL PARTNERSHIP (LIMITED PARTNERSHIP) (CN) | 2024-04-04 | — | — | US | disclosed |
| CN-116670133-A | Alpha protein kinase 1 inhibitors and methods of use | 上海药苑生物科技有限公司 | 2023-08-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226094-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING KAWASAKI DISEASE | PHKA1, PHKA2, PHKG1 | CKS1B 284/4885SKP1 178/4885SKP2 1034/4885 |
| US-20240109853-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS AND METHODS OF USE | PHKA1, PHKA2, PHKG1 | CKS1B 145/4885SKP1 277/4885SKP2 590/4885 |
| US-20250241908-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING ATHEROSCLEROSIS AND RELATED DISEASES | PHKA1, PHKA2, PHKG1 | CKS1B 221/4885SKP1 230/4885SKP2 382/4885 |
| US-20250381196-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING KIDNEY DISEASES AND KIDNEY-RELATED DISEASES | PHKA1, PHKA2, PHKG1 | CKS1B 166/4885SKP1 294/4885SKP2 503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.