Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.53 |
| ▸ | SKP1 | P63208 | 1/20 | 0.53 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 6/20 | 0.48 |
| ▸ | ACACA | Q13085 | 6/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29239235 | 0.89 | CKS1B (0.52) | CKS1BSKP1SKP2DRD2ACACB | |
| SCHEMBL12916519 | 0.88 | GPR119 (0.57) | CKS1BSKP1SKP2SMN1; SMN2DRD2 | |
| SCHEMBL26101401 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2ACYP2C19NAMPT | |
| SCHEMBL16394312 | 0.87 | CKS1B (0.53) | CKS1BSKP1SKP2DRD2ACACB | |
| SCHEMBL5653703 | 0.87 | CKS1B (0.53) | CKS1BSKP1SKP2DRD2ACACB | |
| SCHEMBL8222029 | 0.87 | CKS1B (0.53) | CKS1BSKP1SKP2DRD2ACACB | |
| SCHEMBL4116060 | 0.86 | CKS1B (0.64) | CKS1BSKP1SKP2DRD2ACACB | |
| SCHEMBL17878013 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2ACYP2C19NAMPT | |
| SCHEMBL20946394 | 0.85 | KMT2A (0.55) | SMN1; SMN2MEN1KMT2ACYP2C19NAMPT | |
| SCHEMBL29192701 | 0.85 | MAPT (0.52) | SMN1; SMN2MEN1KMT2ACYP2C19NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226094-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING KAWASAKI DISEASE | XU, Cong (CN) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226094-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING KAWASAKI DISEASE | PHKA1, PHKA2, PHKG1 | CKS1B 284/4885SKP1 178/4885SKP2 1034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.