Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.41 |
| ▸ | TYK2 | P29597 | 3/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23089785 | 0.82 | POLB (0.35) | ALOX5 | |
| SCHEMBL29814732 | 0.82 | POLB (0.35) | ALOX5 | |
| SCHEMBL19283972 | 0.74 | OGA (0.42) | P2RX7 | |
| SCHEMBL30865556 | 0.74 | OGA (0.42) | P2RX7 | |
| SCHEMBL28876638 | 0.73 | AKR1C3 (0.38) | P2RX7 | |
| SCHEMBL31353592 | 0.73 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL29239380 | 0.73 | CCR9 (0.40) | P2RX7 | |
| SCHEMBL29814481 | 0.72 | P2RX7 (0.39) | ALOX5P2RX7 | |
| SCHEMBL23089394 | 0.72 | P2RX7 (0.39) | ALOX5P2RX7 | |
| SCHEMBL30173074 | 0.71 | ALOX5 (0.37) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4380565-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| CN-117915912-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2024-04-19 | — | — | CN | disclosed |
| WO-2023015199-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |