SCHEMBL30173074

SCHEMBL30173074

COC1(c2ccc(Cl)[n+]([O-])c2)CCOC1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23089550 0.84 DRD2 (0.33)
SCHEMBL29814601 0.84 DRD2 (0.33)
SCHEMBL29736489 0.74 ALOX5 (0.35) ALOX5
SCHEMBL23089481 0.74 ALOX5 (0.35) ALOX5
SCHEMBL29239381 0.71 ALOX5 (0.41) ALOX5
SCHEMBL31353592 0.71 ALOX5 (0.42) ALOX5
SCHEMBL9252771 0.66 ALOX5 (0.41) ALOX5
SCHEMBL31353301 0.65 LPL (0.41) ALOX5
SCHEMBL31353191 0.65 LPL (0.41) ALOX5
SCHEMBL31353180 0.65 LPL (0.41) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4380565-A1 HPK1 ANTAGONISTS AND USES THEREOF Nimbus Saturn, Inc. (US) 2024-06-12 EP disclosed
CN-117915912-A HPK1 antagonists and uses thereof 林伯士萨顿公司 2024-04-19 CN disclosed
WO-2023015199-A1 HPK1 ANTAGONISTS AND USES THEREOF Nimbus Saturn, Inc. (US) 2023-02-09 WO disclosed