Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.41 |
| ▸ | HTR1F | P30939 | 4/20 | 0.41 |
| ▸ | HTR1D | P28221 | 3/20 | 0.41 |
| ▸ | HTR1B | P28222 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 3/20 | 0.39 |
| ▸ | PIP5K1C | O60331 | 4/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30173054 | 1.00 | HTR1A (0.41) | HTR1AHTR1FHTR1DHTR1BHPGD | |
| SCHEMBL24992531 | 1.00 | HTR1A (0.41) | HTR1AHTR1FHTR1DHTR1BHPGD | |
| SCHEMBL23103870 | 0.79 | HTR1A (0.47) | HTR1AHTR1FHTR1DHTR1BHPGD | |
| SCHEMBL24993450 | 0.79 | CHRNB2 (0.40) | HTR1ADRD2DRD4 | |
| SCHEMBL30173057 | 0.78 | CHRNB2 (0.35) | — | |
| SCHEMBL30173072 | 0.78 | ADORA2B (0.46) | HTR1AHTR1FHTR1DHTR1BHPGD | |
| SCHEMBL24992530 | 0.78 | ADORA2B (0.46) | HTR1AHTR1FHTR1DHTR1BHPGD | |
| SCHEMBL29239398 | 0.78 | ADORA2B (0.46) | HTR1AHTR1FHTR1DHTR1BHPGD | |
| SCHEMBL23103872 | 0.76 | HPGD (0.50) | HPGDABL1PIP5K1CPIK3CASMN1; SMN2 | |
| SCHEMBL23133828 | 0.74 | HPGD (0.49) | HTR1AHTR1FHTR1DHTR1BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117915912-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2024-04-19 | — | — | CN | disclosed |