Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29239420 | 0.81 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL29239405 | 0.72 | — | — | |
| SCHEMBL29150549 | 0.71 | PARP1 (0.31) | NCEH1 | |
| SCHEMBL28876608 | 0.70 | ALDH1A1 (0.35) | KDM4EALDH1A1MEN1CYP2D6KMT2A | |
| SCHEMBL23089459 | 0.69 | SORT1 (0.34) | KDM4EALDH1A1MEN1CYP1A2CYP2D6 | |
| SCHEMBL23107361 | 0.66 | LCK (0.41) | — | |
| SCHEMBL28662506 | 0.66 | NOTUM (0.35) | MEN1KMT2A | |
| SCHEMBL28657545 | 0.66 | NOTUM (0.35) | MEN1KMT2A | |
| SCHEMBL28666518 | 0.66 | KMT2A (0.34) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11038511 | 0.64 | MEN1 (0.35) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117915912-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2024-04-19 | — | — | CN | disclosed |