Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29239760 | 0.91 | HRH3 (0.34) | L3MBTL1HDAC1HDAC2HDAC6HRH3 | |
| SCHEMBL27833367 | 0.80 | NFKB1 (0.37) | L3MBTL1HDAC1HDAC2HDAC6HRH3 | |
| SCHEMBL28534028 | 0.80 | ALDH1A1 (0.39) | L3MBTL1HDAC1HDAC2HDAC6MEN1 | |
| SCHEMBL28612600 | 0.77 | KMT2A (0.38) | L3MBTL1HDAC1HDAC2HDAC6HRH3 | |
| SCHEMBL27813334 | 0.75 | HRH3 (0.36) | HDAC1HDAC2HDAC6HRH3MEN1 | |
| SCHEMBL1771789 | 0.75 | BTK (0.37) | L3MBTL1HDAC1HDAC2HDAC6HRH3 | |
| SCHEMBL7244461 | 0.71 | HDAC6 (0.39) | L3MBTL1HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL3471151 | 0.71 | CA14 (0.53) | L3MBTL1HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL5070244 | 0.69 | SMN1; SMN2 (0.38) | HRH3MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL5070241 | 0.69 | SMN1; SMN2 (0.38) | HRH3MEN1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591319-B | Tetrahydropyridopyrimidine derivative and application thereof | 江苏先声药业有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-114591319-A | Tetrahydropyridopyrimidine derivative and application thereof | 江苏先声药业有限公司 | 2022-06-07 | — | — | CN | disclosed |