Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1771789 | 0.94 | BTK (0.37) | NFKB1NFKB2RELAKMT2AALDH1A1 | |
| SCHEMBL28612600 | 0.83 | KMT2A (0.38) | NFKB1NFKB2RELAKMT2AALDH1A1 | |
| SCHEMBL29239760 | 0.83 | HRH3 (0.34) | NFKB1NFKB2RELAKMT2AALDH1A1 | |
| SCHEMBL29239679 | 0.80 | L3MBTL1 (0.36) | NFKB1NFKB2RELAKMT2AALDH1A1 | |
| SCHEMBL1829857 | 0.79 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL28534028 | 0.78 | ALDH1A1 (0.39) | NFKB1NFKB2RELAKMT2AALDH1A1 | |
| SCHEMBL27813334 | 0.77 | HRH3 (0.36) | NFKB1NFKB2RELAKMT2AALDH1A1 | |
| SCHEMBL1936374 | 0.77 | HDAC6 (0.39) | NFKB1NFKB2RELAKMT2AALDH1A1 | |
| SCHEMBL9171625 | 0.77 | HDAC6 (0.50) | NFKB1NFKB2RELAKMT2AALDH1A1 | |
| SCHEMBL20496118 | 0.75 | HDAC6 (0.36) | ALDH1A1TSHRHDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102112467-B | Pyrimidine derivative as kinase inhibitors | IRM LLC | 2014-04-30 | — | — | CN | disclosed |
| CN-102112467-A | Compounds and compositions as kinase inhibitors | IRM LLC | 2011-06-29 | — | — | CN | disclosed |