Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717877 | 0.76 | ALDH1A1 (0.40) | — | |
| SCHEMBL232028 | 0.72 | NPSR1 (0.39) | OPRL1OPRD1OPRM1 | |
| SCHEMBL17155053 | 0.71 | OPRL1 (0.37) | OPRL1OPRD1OPRM1 | |
| SCHEMBL2707689 | 0.70 | HCN4 (0.40) | OPRL1OPRD1OPRM1 | |
| SCHEMBL6816556 | 0.70 | NPSR1 (0.41) | OPRL1OPRD1OPRM1 | |
| SCHEMBL25435107 | 0.69 | NPSR1 (0.33) | OPRL1OPRD1OPRM1 | |
| SCHEMBL21877094 | 0.69 | KMT2A (0.34) | OPRL1OPRD1OPRM1 | |
| SCHEMBL16098379 | 0.69 | POLB (0.43) | CHRM1 | |
| SCHEMBL6816871 | 0.69 | NPSR1 (0.44) | OPRL1OPRD1OPRM1 | |
| SCHEMBL31527166 | 0.69 | NPSR1 (0.39) | OPRL1OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591319-B | Tetrahydropyridopyrimidine derivative and application thereof | 江苏先声药业有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-114591319-A | Tetrahydropyridopyrimidine derivative and application thereof | 江苏先声药业有限公司 | 2022-06-07 | — | — | CN | disclosed |