Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KDM4A | O75164 | 5/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29239791 | 0.90 | SMN1; SMN2 (0.34) | DNM1POLBSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL10434741 | 0.82 | SMN1; SMN2 (0.36) | POLBSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL22980572 | 0.79 | CYP1A2 (0.44) | CYP1A2TSHR | |
| SCHEMBL1508731 | 0.76 | MGAM (0.44) | POLBSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL20569336 | 0.75 | FPR3 (0.37) | — | |
| SCHEMBL23007925 | 0.74 | CYP1A2 (0.42) | CYP1A2SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL8643850 | 0.74 | TSHR (0.44) | CYP1A2TSHR | |
| SCHEMBL13123496 | 0.73 | MGAM (0.37) | POLBSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL8640267 | 0.73 | TSHR (0.46) | CYP1A2TSHR | |
| SCHEMBL25866514 | 0.72 | CYP1A2 (0.43) | CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591319-B | Tetrahydropyridopyrimidine derivative and application thereof | 江苏先声药业有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-114591319-A | Tetrahydropyridopyrimidine derivative and application thereof | 江苏先声药业有限公司 | 2022-06-07 | — | — | CN | disclosed |