Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29239790 | 0.90 | DNM1 (0.36) | SMN1; SMN2ALDH1A1MEN1KMT2ADNM1 | |
| SCHEMBL10434741 | 0.81 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1MEN1KMT2AMGAM | |
| SCHEMBL20569336 | 0.80 | FPR3 (0.37) | — | |
| SCHEMBL1508731 | 0.78 | MGAM (0.44) | SMN1; SMN2ALDH1A1MEN1KMT2AMGAM | |
| SCHEMBL22980572 | 0.75 | CYP1A2 (0.44) | MGAMGAASIMGAM2 | |
| SCHEMBL13123496 | 0.75 | MGAM (0.37) | SMN1; SMN2ALDH1A1MEN1KMT2AMGAM | |
| SCHEMBL9781822 | 0.74 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1MEN1KMT2AMGAM | |
| SCHEMBL2787784 | 0.72 | MGAM (0.41) | SMN1; SMN2ALDH1A1MEN1KMT2AMGAM | |
| SCHEMBL8640882 | 0.71 | TSHR (0.39) | SMN1; SMN2ALDH1A1MEN1KMT2AMGAM | |
| Hydrochloric Acid SCHEMBL2787783 | 0.71 | MGAM (0.39) | SMN1; SMN2ALDH1A1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591319-B | Tetrahydropyridopyrimidine derivative and application thereof | 江苏先声药业有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-114591319-A | Tetrahydropyridopyrimidine derivative and application thereof | 江苏先声药业有限公司 | 2022-06-07 | — | — | CN | disclosed |