Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | TOP2A | P11388 | 1/20 | 0.53 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25434643 | 1.00 | NPSR1 (0.60) | NPSR1APEX1TOP2ALGALS8ALDH1A1 | |
| SCHEMBL28057569 | 0.94 | NPSR1 (0.56) | NPSR1APEX1TOP2ALGALS8ALDH1A1 | |
| SCHEMBL29491599 | 0.90 | NPSR1 (0.47) | NPSR1APEX1TOP2ALGALS8ALDH1A1 | |
| SCHEMBL25435624 | 0.86 | ALDH1A1 (0.51) | NPSR1APEX1LGALS8ALDH1A1MAPK1 | |
| SCHEMBL13544348 | 0.77 | NPSR1 (0.97) | NPSR1APEX1TOP2ALGALS8ALDH1A1 | |
| SCHEMBL29262338 | 0.76 | MAPT (0.47) | ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL29924789 | 0.76 | HTT (0.36) | NPSR1LGALS8ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL30487057 | 0.76 | HTT (0.36) | NPSR1LGALS8ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL5396738 | 0.76 | NPSR1 (0.73) | NPSR1APEX1TOP2ALGALS8ALDH1A1 | |
| SCHEMBL30174410 | 0.74 | GABRA1 (0.41) | LGALS8ALDH1A1MAPK1SMN1; SMN2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4069686-B1 | GLP-1 RECEPTOR AGONIST | HYUNDAI PHARM CO LTD (KR) | 2025-01-22 | — | — | EP | disclosed |
| CN-115515956-B | Benzimidazole derivative, and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-06-25 | — | — | CN | disclosed |