Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 5/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DTYMK | P23919 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29242116 | 0.84 | POLB (0.54) | POLBPARP1GPR119MEN1KMT2A | |
| SCHEMBL29086062 | 0.81 | GPR119 (0.53) | POLBPARP1GPR119MEN1KMT2A | |
| SCHEMBL21921216 | 0.80 | POLB (0.55) | POLBGPR119KMT2A | |
| SCHEMBL11892882 | 0.80 | POLB (0.60) | POLBPARP1GPR119DTYMKCKS1B | |
| SCHEMBL27061355 | 0.79 | POLB (0.54) | POLBGPR119DTYMKCKS1BSKP1 | |
| SCHEMBL28585097 | 0.76 | GPR119 (0.53) | POLBPARP1GPR119MEN1KMT2A | |
| SCHEMBL1379678 | 0.76 | PARP1 (0.56) | PARP1MAPT | |
| SCHEMBL30040285 | 0.76 | PARP1 (0.56) | PARP1MAPT | |
| SCHEMBL6979526 | 0.75 | POLB (0.52) | POLBPARP1GPR119 | |
| SCHEMBL7710611 | 0.75 | PTPN2 (0.57) | POLBPARP1GPR119KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271285-A | Azetidine-containing amide derivative, preparation method and application thereof | 贵州大学 | 2024-07-02 | — | — | CN | disclosed |