Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | DTYMK | P23919 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29242060 | 0.81 | POLB (0.56) | GPR119POLBMEN1KMT2ACKS1B | |
| SCHEMBL18123360 | 0.81 | POLB (0.65) | GPR119POLBMEN1KMT2ACKS1B | |
| SCHEMBL28585097 | 0.80 | GPR119 (0.53) | GPR119POLBMEN1KMT2ACKS1B | |
| SCHEMBL29242116 | 0.79 | POLB (0.54) | GPR119POLBMEN1KMT2ACKS1B | |
| SCHEMBL27340911 | 0.79 | GPR119 (0.70) | GPR119POLBMEN1KMT2ACKS1B | |
| SCHEMBL861278 | 0.78 | USP2 (0.64) | GPR119MEN1KMT2AHPGDMAPT | |
| 2-Aminopyridine SCHEMBL28443400 | 0.77 | GPR119 (0.55) | GPR119POLBMEN1KMT2ACKS1B | |
| SCHEMBL29461540 | 0.77 | GPR119 (0.76) | GPR119POLBCKS1BSKP1SKP2 | |
| SCHEMBL30585735 | 0.77 | P2RX7 (0.37) | POLBMEN1KMT2AHPGD | |
| SCHEMBL30808538 | 0.76 | GPR119 (0.55) | GPR119POLBMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520422-B | Novel pyridonecarboxylic acid derivative or salt thereof | 涌永制药株式会社 | 2023-09-05 | — | — | CN | disclosed |