Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 6/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27455546 | 0.98 | LMNA (0.44) | LMNASMN1; SMN2TXNRD1MTNR1AMTNR1B | |
| Water SCHEMBL27347655 | 0.96 | LMNA (0.43) | LMNASMN1; SMN2TXNRD1MTNR1AMTNR1B | |
| SCHEMBL7270618 | 0.81 | SMN1; SMN2 (0.60) | LMNASMN1; SMN2TXNRD1MTNR1AMTNR1B | |
| SCHEMBL28888991 | 0.80 | LMNA (0.44) | LMNASMN1; SMN2TXNRD1MTNR1AMTNR1B | |
| SCHEMBL5365940 | 0.75 | LMNA (0.40) | LMNASMN1; SMN2TXNRD1MTNR1AMTNR1B | |
| SCHEMBL9528691 | 0.75 | HCRTR1 (0.36) | TXNRD1MTNR1AMTNR1BHCRTR1HCRTR2 | |
| SCHEMBL27698646 | 0.73 | NPSR1 (0.41) | LMNASMN1; SMN2POLBTDP1 | |
| SCHEMBL28888968 | 0.72 | MAPK1 (0.52) | LMNASMN1; SMN2TXNRD1S1PR1 | |
| SCHEMBL27715997 | 0.71 | KDM4E (0.36) | LMNASMN1; SMN2TDP1 | |
| SCHEMBL3467323 | 0.70 | LOX (0.46) | LMNASMN1; SMN2LOXLOXL2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215806-B | Synthesis method of sulfanilamide-6-methoxypyrimidine | 江苏天和制药有限公司 | 2024-03-29 | — | — | CN | disclosed |