Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28888991 | 0.77 | LMNA (0.44) | MAPK1HTTS1PR4MAPTS1PR1 | |
| SCHEMBL7270618 | 0.75 | SMN1; SMN2 (0.60) | S1PR1NPSR1ALDH1A1TXNRD1KDM4E | |
| SCHEMBL27455546 | 0.74 | LMNA (0.44) | S1PR1TXNRD1SMN1; SMN2LMNA | |
| Water SCHEMBL27347655 | 0.72 | LMNA (0.43) | S1PR1TXNRD1SMN1; SMN2LMNA | |
| SCHEMBL29242561 | 0.72 | LMNA (0.43) | S1PR1TXNRD1SMN1; SMN2LMNA | |
| SCHEMBL2130866 | 0.69 | MEN1 (0.51) | MAPTCYP3A4L3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL5365940 | 0.69 | LMNA (0.40) | MAPK1HTTS1PR4MAPTS1PR1 | |
| SCHEMBL18497236 | 0.69 | S1PR4 (1.00) | MAPK1HTTS1PR4MAPTS1PR1 | |
| SCHEMBL61299 | 0.68 | — | — | |
| SCHEMBL8686519 | 0.68 | LMNA (0.55) | HTTMAPTHSP90AA1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215806-A | Method for synthesizing sulfanilamide-6-methoxypyrimidine | 江苏天和制药有限公司 | 2022-10-21 | — | — | CN | disclosed |