Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 4/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16818755 | 0.74 | BRD4 (0.49) | BRD4 | |
| SCHEMBL1935026 | 0.73 | KDR (0.42) | CDK8ROCK1CHEK1MAP4K4CSF1R | |
| SCHEMBL19410802 | 0.69 | CDK8 (0.38) | CDK8ROCK1CHEK1MAP4K4CSF1R | |
| SCHEMBL557383 | 0.69 | MAP2K1 (0.44) | CDK8ROCK1CHEK1MAP4K4CSF1R | |
| SCHEMBL20767747 | 0.67 | CDK8 (0.36) | CDK8ROCK1CHEK1MAP4K4CSF1R | |
| SCHEMBL1104796 | 0.65 | ROCK1 (0.46) | BRD4CDK8ROCK1CHEK1MAP4K4 | |
| SCHEMBL6512398 | 0.65 | CCNE1 (0.33) | CDK8ROCK1CHEK1MAP4K4CSF1R | |
| SCHEMBL16244139 | 0.64 | RPS6KA5 (0.47) | CDK8ROCK1CHEK1MAP4K4CSF1R | |
| SCHEMBL24896311 | 0.62 | RAB9A (0.49) | BRD4MAP2K1MAPT | |
| SCHEMBL1599283 | 0.61 | MAPT (0.38) | CDK8ROCK1CHEK1MAP4K4CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240294529-A1 | 6H-IMIDAZO[1,2-A]PYRROLO[2,3-E]PYRIDINE DERIVATIVES FOR USE IN THERAPY | SANOFI (FR) | 2024-09-05 | — | — | US | disclosed |
| US-20240294529-A1 | 6H-IMIDAZO[1,2-A]PYRROLO[2,3-E]PYRIDINE DERIVATIVES FOR USE IN THERAPY | SANOFI (FR) | 2024-09-05 | — | — | US | disclosed |
| CN-118234727-A | 6H-imidazo [1,2-a ] pyrrolo [2,3-e ] pyridine derivatives for use in therapy | 赛诺菲 | 2024-06-21 | — | — | CN | disclosed |
| CN-118234727-A | 6H-imidazo [1,2-a ] pyrrolo [2,3-e ] pyridine derivatives for use in therapy | 赛诺菲 | 2024-06-21 | — | — | CN | disclosed |
| EP-4373337-A1 | VAPOUR GENERATING DEVICE | JT International SA (CH) | 2024-05-29 | — | — | EP | disclosed |
| EP-4370516-A1 | 6H-IMIDAZO[1,2-A]PYRROLO[2,3-E]PYRIDINE DERIVATIVES FOR USE IN THERAPY | Sanofi (FR) | 2024-05-22 | — | — | EP | disclosed |
| EP-4370516-A1 | 6H-IMIDAZO[1,2-A]PYRROLO[2,3-E]PYRIDINE DERIVATIVES FOR USE IN THERAPY | Sanofi (FR) | 2024-05-22 | — | — | EP | disclosed |
| WO-2023285465-A1 | 6H-IMIDAZO[1,2-A]PYRROLO[2,3-E]PYRIDINE DERIVATIVES FOR USE IN THERAPY | SANOFI (FR) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023285465-A1 | 6H-IMIDAZO[1,2-A]PYRROLO[2,3-E]PYRIDINE DERIVATIVES FOR USE IN THERAPY | SANOFI (FR) | 2023-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294529-A1 | 6H-IMIDAZO[1,2-A]PYRROLO[2,3-E]PYRIDINE DERIVATIVES FOR USE IN THERAPY | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, AKR1C3, CBR3 | BRD4 298/4885CDK8 1747/4885ROCK1 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.